Ethyl acetate extract of Ruta graveolens: a specific and potent inhibitor against the drug-resistant EGFR_T790M mutant in NSCLC
Lung cancer, the second leading cause trailmaster challenger 200x of cancer mortality, requires the development of novel therapeutic strategies due to emerging drug resistance and toxicity.With this objective, the present work explored the therapeutic potential of R.graveolens leaf extracts against EGFR_T790M-mediated drug resistance in NSCLC.To th