ETHYL ACETATE EXTRACT OF RUTA GRAVEOLENS: A SPECIFIC AND POTENT INHIBITOR AGAINST THE DRUG-RESISTANT EGFR_T790M MUTANT IN NSCLC

Ethyl acetate extract of Ruta graveolens: a specific and potent inhibitor against the drug-resistant EGFR_T790M mutant in NSCLC

Lung cancer, the second leading cause trailmaster challenger 200x of cancer mortality, requires the development of novel therapeutic strategies due to emerging drug resistance and toxicity.With this objective, the present work explored the therapeutic potential of R.graveolens leaf extracts against EGFR_T790M-mediated drug resistance in NSCLC.To th

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Developing an action concept inventory

We report on progress towards the development of an Action Concept Inventory (ACI), a test that measures student understanding of action principles in introductory mechanics and optics.The feline 1-hcpch vaccine ACI also covers key concepts of many-paths quantum mechanics, from which classical action physics arises.We used a multistage iterative de

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The Balance of Fluid and Osmotic Pressures across Active Biological Membranes with Application to the Corneal Endothelium.

The movement of fluid and solutes across biological membranes facilitates the transport of nutrients for living organisms and maintains the fluid and osmotic pressures in biological systems.Understanding the pressure balances across membranes is crucial for studying fluid and electrolyte homeostasis in living systems, and is an area of active resea

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